教員紹介

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著書

1. 茶の効能と応用開発，脳機能障害抑制, (pp174-184), 2006, シーエムシー出版
2. 免疫と栄養－食と薬の融合，中枢神経の病変, (pp162-179), 2006, シーエムシー出版
3. 抗ストレス食品の開発と展望II，アミノ酸・ペプチド・タンパク質 , (pp117-121), 2012, シーエムシー出版
4. 機能性アミノ酸・ペプチドの技術と市場，機能性アミノ酸・ペプチド‐神経伝達物質としてのアミノ酸, (pp22-33) , 2012シーエムシー出版
5. 新版茶の機能‐ヒト試験から分かった新たな役割，老化と認知症, (pp259-265), 2013, 農山漁村文化協会
6. アミノ酸科学の最前-基礎研究を活かした応用戦-，注目のアミノ酸とその応用, 5テアニン (pp258-264), 2014, シーエムシー出版
7. 機能性食品開発のための初期評価試験プロトコール集（pp173-187）, 2017, シーエムシー出版

総説

1. お茶と脳機能－病気予防からリラックスまで－食品と容器,　No.46494-501, p26-31, 2005.
2. 老化に伴う脳疾患への食品栄養科学的アプローチ 生物と科学, 44, p603-608, 2006.
3. FDG-PET画像解析にMCIからADへの移行予測能の可能性Medical Tribune, 43, p40, 2010.
4. FDG-PETによる認知症診断：3D-SSPとAD t-sum. 特集２：認知症診断における統計画像PETジャーナル summer(14), p23-25, 2011.
5. ミルクセラミド(MC-5)の記憶学習への影響Food Style 21, 19(10), p47-50, 2015.

論文

1. Effects of thenaine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission. Nutritional Neuroscience 8, p219-226, 2005.
2. Theanine, r-Glutamyl- ethylamide, increases neurotransmission concentrations and neurotrophin mRNA levels in the brain during lactation. Life Sciences 81, p1247-1255, 2007.
3. Administration of theanine, a unique amino acid in tea leaves, changed feeding-relating components in the serum and feeding behavior in rats. Bioscience Biotechnology and Biochemistry 72, p1352-1355, 2008.
4. Effects of theanine, a unique amino acid in tea leaves, on memory in a rat behavioral test. Bioscience Biotechnology and Biochemistry 72, p1356-1359, 2008.
5. Effects intracerebral microinjection and intra- peritoneal injection of [60]- fullerene on brain functions differ in rats. Journal of Nanoscience and Nanotechnology 8, p3973-3980, 2008.
6. Role of estrogen receptors and aromatase on brain protein synthesis rates in ovariectomized female rats fed genistein.　Nutritional Neuroscience 11, p155-160, 2008.
7. The effect of sulfated hyaluronan on the morphological transformation and activity of cultured human astrocytes. Biomaterials 29, p3503-3513, 2008.
8. Intracerebral microinjection of stannous 2-ethylhexanoate affects dopamine turnover in cerebral cortex and locomotor activity in rats. Journal of Biomedical Materials Research Parr B Applied Biomater.ials, 87, p381-386, 2008.
9. Theanine, r-glutamylethylamide a unique amino acid in tea leaves, modulates some neurotransmitter concentration in the brain striatum interstitium and the mechanism in conscious rats. Amino Acids 36, p21-27, 2009.
10. 新無血清培地STK2のヒト間葉系幹細胞増殖における有効性について. 薬学雑誌, 129, p381-384, 2009.
11. V79細胞および正常ヒトアストロサイトとカーボンナノチューブおよびその誘導体の細胞毒性. 国立医薬品食品衛生研究所報告, 127: p39-43, 2009.
12. Anxiolytic effects of acute and chronic administrations of cacao mass in rats elevated T-maze test. The Journal of Nutritional Biochemistry, 20, p948-955, 2009.
13. Effects of intracerebral microinjection of hydroxylated- [60]fullerene on brain monoamine concentrations and locomotor behavior in rats. Journal of Nanoscience and Nanotechnology 10, p604-611, 2010.
14. Effects of cell-seeding methods of human osteoblast culture on biomechanical properties of porous bioceramic scaffold. Biotechnology and Bioprocess Engineering, 15, p341-348, 2010.
15. 小動物における定量的画像解析. 脳循環代謝 21, p50-57, 2010.
16. ヒト間葉系幹細胞の網羅的遺伝子発現解析－無血清培地を用いたin vitro培養期間中の遺伝子発現の変化について－. 薬学雑誌 130, p1387-1393, 2010.
17. Evaluation of neurotoxicity of artificaial dura mater and dura mater containing a high concentration of dibutyltin in rats after intracranial implantation. Kitasato Medicine Journal, 42, p67-75, 2010.
18. Dietary ornithine affects the tissue protein synthesis rate in young rats. Journal of Nutrition Science and Vitaminology, 58(4), p297-302, 2012.
19. Effect of dietary ornithine on the brain protein synthesis rate in hypophysectomized aged rats. Journal of Nutrition Science and Vitaminology, 58(5), p346-353, 2013.
20. Novel system using microliter order sample volume for measuring arterial radioactivity concentrations in whole blood and plasma for mouse PET dynamic study. Physics in Medicine and Biology, 58(22), p7889-7903, 2013.
21. Effect of dietary　-aminobutyric acid on the nerve growth factor and the choline acetyltransferase in the cerebral cortex and hippocampus of ovariectomized female rats. Journal of Nutrition Science and Vitaminology, 60(1), p60-65, 2014.
22. Radiosynthesis and in vivo evaluation of two imidazopyridineacetamides, [11C] CB184 and [11C]　CB190, as a PET tracer for 18 kDa translocator protein: direct comparison with [11C](R)-PK11195. Annals of Nuclear Medicine, 29(4), p325-335, 2015.
23. 痛風高尿酸血症における脂肪肝の検討. 痛風と核酸代謝, 39(1), p98, 2015.
24. 痛風高尿酸血症における耐糖能異常の検討. 痛風と核酸代謝, 39(1), p99, 2015.
25. Comparison of the effects of ornithine and arginine on the brain protein synthesis rate in young rats. Journal of Nutrition Science and Vitaminology, 61(5), p417-421, 2015.
26. Synthesis of PET probe O6-[(3-[11C]methyl)benzyl]guanine by　Pd0-mediated rapid C-[11C]methylation toward imaging DNA repair protein O6-methylguanine-DNA methyltransferase in glioblastoma. Bioorganic and Medicinal Chemistry Letters, 27(9), p1892-1896, 2017
27. 3,5,6,7,8,3′,4′-Heptamethoxyflavone Ameliorates Depressive-Like Behavior and Hippocampal Neurochemical Changes in Chronic Unpredictable Mild Stressed Mice by Regulating the Brain-Derived Neurotrophic Factor: Requirement for ERK Activation. International Journal of Molecular Sciences, 18(10), 2133-2148, 2017
28. Changes in Thyroid Hormone Are Not Involved in Regulating Brain Protein Synthesis in Adults Rats Fed Ornithine. Journal of Nutrition Science and Vitaminology, 63(6), p389-395, 2017.
29. Microliter-ordered automatic blood sampling system for fully quantitative analysis of small-animal PET. Annals of nuclear medicine, 33(8), p586-593, 2019.
30. Brain pharmacokinetics and biodistribution of 11C-labeled isoproterenol in rodents. Nuclear Medicine and Biology, 86-87, p52-58, 2020.
31. Peripheral benzodiazepine receptor/ 18kDa translocator protein positron emission tomography imaging in a rat model of acute brain injury. Annals of nuclear medicine, 35(1), p8-16, 2021.